Affiliate and associate members are appointed in various Departments and hospitals, including the Department of Anatomy and Cell Biology, Biochemistry, Biology, Human Genetics, Medicine, Microbiology and Immunology, Oncology, Pediatrics, Pharmacology and Therapeutics, the Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal Children's Research Institute, Montreal General Hospital, National Institute on Aging, St. Michael's Hospital, and the World Health Organization.

The Centre maintains very close bonds with the numerous departments and hospitals. These affiliations provide the Centre with first-rate academic infrastructure required for the training and management of its students and researchers.All GCRC members have access to common areas, cutting edge equipment, core facilities and resources.

Dr. Clifford Stanners

Research Summary
Molecular and Cellular Biology of Human Carcinoembryonic Antigen (CEA)

Affiliation
Professor Emeritus. Department of Biochemistry
McGill University
Associate Member - Emeritus, Goodman Cancer Research Centre

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Dr. Maria Zannis-Hadjopoulos

Dr. Maria Zannis-Hadjopoulos, Goodman Cancer Research Centre

Research Summary
Mammalian origins of DNA replication, interacting sequence- and structure-specific proteins and role of cruciform structures in the initiation of mammalian DNA replication.

Affiliation
Emerita, Goodman Cancer Research Centre

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Dr. Moulay Alaoui-Jamali
Cancer & Target Discovery; Screening for Novel Therapeutics.
Dr. Pnina Brodt
Molecular mechanisms of cancer metastasis, role of inflammation and the tumor microenvironment; developing novel strategies for the prevention and treatment of metastases.
Dr. Jörg Fritz
Understanding how innate host resistance regulates inflammatory and antigen-specific adaptive immune responses.
Dr. Antonis Koromilas
Control of protein synthesis, environmental stress, tumor suppressor genes, oncogenes, signal transduction, protein phosphorylation, breast cancer, chemotherapeutic drugs.
Dr. David P. Labbé 
Prostate cancer, Nutrition/diet, Epigenetics, Animal models, Translational research
Dr. Nathalie Lamarche-Vane
My laboratory investigates the molecular mechanisms regulated by the Rho family of GTPases, playing a crucial role in a plethora of cellular functions. In particular, we are interested to delineate the roles of Rho GTPases in cell motility and cell migration, such as axon guidance during the development of the nervous system or in cancer cell migration.
Dr. Paul Lasko
Oogenesis and pole plasm assembly using the model organism Drosophila melanogaster.
Dr. Carmen Loiselle
Differential cancer information-seeking behaviours, self-regulation, and psychosocial adjustment to cancer.
Dr. Richard Marcotte
The interface between engineering, biology and medicine.
Dr. Michael Pollak
Roles of peptide growth factors, particularly insulin-like growth factors (IGFs), in the pathophysiology of neoplasia.
Dr. Janusz Rak
Tumor angiogenesis and anti-angiogenesis. The role of oncogenes in angiogenic and procoagulant events in cancer, particularly in pediatric patient population. Age related changes in responsiveness/resistance to antiangiogenic agents.
Dr. Yasser Riazalhosseini
Integrative genome analysis of cancer cells; analysis of tumor heterogeneity; cancer gene regulatory programs.
Dr. Clifford Stanners
Molecular and Cellular Biology of Human Carcinoembryonic Antigen (CEA).
Dr. Patricia Tonin
Genetic factors implicated in the development and/or progression of human epithelial ovarian cancers, genetic factors that predispose to hereditary forms of breast and ovarian cancers.
 

Dr. Moulay Alaoui-Jamali

Research Summary
Cancer & Target Discovery; Screening for Novel Therapeutics.

Affiliation
Departments of Medicine and Oncology, McGill University
FRSQ Research Scholar
Associate Member, Goodman Cancer Research Centre

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Dr. Pnina Brodt

Research Summary
Molecular mechanisms of cancer metastasis, role of inflammation and the tumor microenvironment;  developing novel strategies for the prevention and treatment of  metastases.

Affiliation
Departments of Surgery, Medicine & Oncology, McGill University and the McGill University Health Center
Associate Member, Goodman Cancer Research Centre

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Dr. Jörg Hermann Fritz

Research Summary
Understanding how innate host resistance regulates inflammatory and antigen-specific adaptive immune responses.

Affiliation
Associate Professor, Department of Microbiology and Immunology
McGill University
Associate Member, Goodman Cancer Research Centre
 

 

Antonis Koromilas, PhD

Research Summary
Control of protein synthesis, environmental stress, tumor suppressor genes, oncogenes, signal transduction, protein phosphorylation, breast cancer, chemotherapeutic drugs.

Affiliation
Department of Oncology, McGill University
Associate Member, Goodman Cancer Research Centre

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Dr. David P. Labbé

David Labbe

Research Summary
Systemic metabolic alterations associated with increased consumption of saturated fat and obesity are linked with increased risk of prostate cancer progression and mortality, but the molecular underpinnings of this association are poorly understood. My research program is aimed at understanding the combination of key tumour genetic alterations together with the host characteristics required for diet to alter prostate cancer progression. This will allow the identification of new therapeutic targets and the elaboration of novel therapeutic approaches devised to treat prostate cancer patients at risk of progression to an aggressive, lethal disease. More specifically, my research focuses on the mechanisms and therapeutic targets related to epigenetic alterations and uses murine and human cell lines, animal models (including genetically engineered mouse models) and human tissues.

Affiliation
Assistant Professor, Department of Surgery, Division of Urology, McGill University
Associate Member, Department of Medicine, Division of Experimental Medicine, McGill University
Associate Member, Goodman Cancer Research Centre

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Dr. Nathalie Lamarche-Vane

Research Summary
My laboratory investigates the molecular mechanisms regulated by the Rho family of GTPases, playing a crucial role in a plethora of cellular functions. In particular, we are interested to delineate the roles of Rho GTPases in cell motility and cell migration, such as axon guidance during the development of the nervous system or in cancer cell migration.

Affiliation
McGill University Health Center
Department of Anatomy and Cell Biology
Associate Member, Goodman Cancer Research Centre

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Dr. Paul Lasko

Research Summary
Oncogenesis and pole plasm assembly using the model organism Drosophila melanogaster.

Affiliation
Department of Biology, McGill University
Associate Member, Goodman Cancer Research Centre

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Dr. Carmen Loiselle

Research Summary
Differential cancer information-seeking behaviours, self-regulation, and psychosocial adjustment to cancer.

Affiliation
Professor, Oncology Department and Ingram School of Nursing, McGill University
Christine and Hershel Victor/Hope and Cope Chair in Psychosocial Oncology
Director, McGill University Oncology Nursing Program and Psychosocial Oncology
Associate Member, Rosalind & Morris Goodman Cancer Research Centre
Co-Director (Academic) of the Segal Cancer Centre, Jewish General Hospital
Scientific Director of Hope & Cope, Jewish General Hospital

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Dr. Richard Marcotte

Research Summary
The identification of therapeutic cancer target using high-throughput functional genomic approaches.

Affiliation
Project Leader-Primary Assay Team
Human Health Therapeutics Portfolio, National Research Council Canada
http://www.nrc-cnrc.gc.ca/eng/rd/hht/
Associate Member, Goodman Cancer Research Centre
McGill University

Dr. Michael Pollak

Research Summary
Roles of peptide growth factors, particularly insulin-like growth factors (IGFs), in the pathophysiology of neoplasia.

Affiliation
Professor, Department of Medicine & Oncology, McGill University
Director, Cancer Prevention Centre, SMBD-Jewish General Hospital
Alexander Goldfarb Research Chair in Medical Oncology
Associate Member, Goodman Cancer Research Centre

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Dr. Janusz Rak

Research Summary
Tumor angiogenesis and anti-angiogenesis. The role of oncogenes in angiogenic and procoagulant events in cancer, particularly in pediatric patient population. Age related changes in responsiveness/resistance to antiangiogenic agents.

Affiliation
Department of Pediatrics
McGill University
Montreal Children's Hospital Research Institute
Associate Member, Goodman Cancer Research Centre

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Dr. Yasser Riazalhosseini

Research Summary
Integrative genome analysis of cancer cells
Analysis of tumor heterogeneity
Cancer gene regulatory programs

Affiliation
Assistant Professor, Department of Human Genetics, McGill University
Principal investigator, McGill University and Génome Québec Innovation Centre
Associate Member, Goodman Cancer Research Centre

 

Dr. Julie St-Pierre

Affiliation
Associate Professor, Department of Biochemistry, Microbiology and Immunology
University of Ottawa
Associate Member, Goodman Cancer Research Centre

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Dr. Clifford Stanners

Research Summary
Molecular and Cellular Biology of Human Carcinoembryonic Antigen (CEA)

Affiliation
Professor Emeritus. Department of Biochemistry
McGill UNiversity
Associate Member - Emeritus, Goodman Cancer Research Centre

 

Dr. Patricia Tonin

Research Summary
Genetic factors implicated in the development and/or progression of human epithelial ovarian cancers, genetic factors that predispose to hereditary forms of breast and ovarian cancers.

Affiliation
Department of Medicine and Human Genetics
The Research Institute of the McGill University Health Centre Medicine
Associate Member, Goodman Cancer Research Centre

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