Ma EH, Bantug G, Griss T, Condotta S, Johnson RM, Samborska B, Mainolfi N, Suri V, Guak H, Balmer ML et al: Serine Is an Essential Metabolite for Effector T Cell Expansion. Cell Metab 2017.

Audet-Walsh É, Yee T, McGuirk S, Vernier M, Ouellet C, St-Pierre J, Giguère V: Androgen-Dependent Repression of ERRγ Reprograms Metabolism in Prostate Cancer. Cancer Research 2017.

Yan M, Audet-Walsh É, Manteghi S, Rosa Dufour C, Walker B, Baba M, St-Pierre J, Giguère V, Pause A: Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα. Genes Dev 2016, 30(9):1034-1046.

Yachnin BJ, Lau PCK, Berghuis AM: The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2016, 1864(12):1641-1648.

Rone MB, Cui Q-L, Fang J, Want L-C, Khan D, Bedard M, Almazan G, Ludwin SK, Jones R, Kennedy TE et al: Oligodendrogliopathy in Multiple Sclerosis: Low Glycolytic Metabolic Rate Promotes Oligodendrocyte Survival. The Journal of Neuroscience 2016, 36(17):4698-4707.

Reimer JM, Aloise MN, Harrison PM, Martin Schmeing T: Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase. Nature 2016, 529(7585):239-242.

Liu Z, Yokoyama NN, Blair CA, Li X, Avizonis D, Wu X-R, Uchio E, Youssef R, McClelland M, Pollak M et al: High Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ∼240-Fold Higher Drug Concentration in Urine than Serum. Molecular Cancer Therapeutics 2016, 15(3):430-438.

Lampropoulou V, Sergushichev A, Bambouskova M, Nair S, Vincent Emma E, Loginicheva E, Cervantes-Barragan L, Ma X, Huang Stanley C-C, Griss T et al: Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation. Cell Metab 2016, 24(1):158-166.

Izreig S, Samborska B, Johnson Radia M, Sergushichev A, Ma Eric H, Lussier C, Loginicheva E, Donayo Ariel O, Poffenberger Maya C, Sagan Selena M et al: The miR-17∼92 microRNA Cluster Is a Global Regulator of Tumor Metabolism. Cell Reports 2016, 16(7):1915-1928.

Gravel S-P, Avizonis D, St-Pierre J: Metabolomics Analyses of Cancer Cells in Controlled Microenvironments. In: The Tumor Microenvironment: Methods and Protocols. Edited by Ursini-Siegel J, Beauchemin N. New York, NY: Springer New York; 2016: 273-290.

Deblois G, Smith HW, Tam IS, Gravel S-P, Caron M, Savage P, Labbe DP, Begin LR, Tremblay ML, Park M et al: ERR[alpha] mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nat Commun 2016, 7.

Chandel Navdeep S, Avizonis D, Reczek Colleen R, Weinberg Samuel E, Menz S, Neuhaus R, Christian S, Haegebarth A, Algire C, Pollak M: Are Metformin Doses Used in Murine Cancer Models Clinically Relevant? Cell Metab 2016, 23(4):569-570.

Carbonneau M, M. Gagné L, Lalonde M-E, Germain M-A, Motorina A, Guiot M-C, Secco B, Vincent EE, Tumber A, Hulea L et al: The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nature Communications 2016, 7:12700.

Boukhaled Giselle M, Cordeiro B, Deblois G, Dimitrov V, Bailey Swneke D, Holowka T, Domi A, Guak H, Chiu H-Hsuan C, Everts B et al: The Transcriptional Repressor Polycomb Group Factor 6, PCGF6, Negatively Regulates Dendritic Cell Activation and Promotes Quiescence. Cell Reports 2016, 16(7):1829-1837.

Balmer Maria L, Ma Eric H, Bantug Glenn R, Grählert J, Pfister S, Glatter T, Jauch A, Dimeloe S, Slack E, Dehio P et al: Memory CD8+ T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function. Immunity 2016, 44(6):1312-1324.

Audet-Walsh É, Papadopoli David J, Gravel S-P, Yee T, Bridon G, Caron M, Bourque G, Giguère V, St-Pierre J: The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Cell Reports 2016, 14(4):920-931.

Aaron C, Beaudry G, Parker JA, Therrien M: Maple Syrup Decreases TDP-43 Proteotoxicity in a Caenorhabditis elegans Model of Amyotrophic Lateral Sclerosis (ALS). Journal of Agricultural and Food Chemistry 2016, 64(17):3338-3344.


         El-Assaad W, El-Kouhen K, Mohammad A, Yang J, Morita M, Gamache I, Mamer O, Avizonis D, Hermance N, Kersten S et al: Deletion of the gene encoding G0/G1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice. Diabetologia 2014:1-9.

        Chan M, Gravel M, Bramoulle A, Bridon G, Avizonis D, Shore GC, Roulston A: Synergy between the NAMPT inhibitor GMX1777(8) and pemetrexed in non-small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption. Cancer Research 2014

        Everts B, Amiel E, Huang SC-C, Smith AM, Chang C-H, Lam WY, Redmann V, Freitas TC, Blagih J, van der Windt GJW et al: TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKepsilon supports the anabolic demands of dendritic cell activation. Nat Immunol 2014, 15(4):323-332.

        Gravel S-P, Hulea L, Toban N, Birman E, Blouin M-J, Zakikhani M, Zhao Y, Topisirovic I, St-Pierre J, Pollak M: Serine Deprivation Enhances Antineoplastic Activity of Biguanides. Cancer Research 2014, 74(24):7521-7533.

        Perry M-C, Dufour CR, Tam IS, B'Chir W, Giguère V: Estrogen-Related Receptor-alpha Coordinates Transcriptional Programs Essential for Exercise Tolerance and Muscle Fitness. Molecular Endocrinology 2014, 28(12):2060-2071.

        Yan M, Gingras M-C, Dunlop EA, Nouët Y, Dupuy F, Jalali Z, Possik E, Coull BJ, Kharitidi D, Dydensborg AB et al: The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation. The Journal of Clinical Investigation 2014, 124(6):2640-2650.

        Wynosky-Dolfi MA, Snyder AG, Philip NH, Doonan PJ, Poffenberger MC, Avizonis D, Zwack EE, Riblett AM, Hu B, Strowig T: Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome. The Journal of experimental medicine 2014, 211(4):653-668.

        Vincent EE, Coelho PP, Blagih J, Griss T, Viollet B, Jones RG: Differential effects of AMPK agonists on cell growth and metabolism. (advanced on-line publication) Oncogene 2014.

        Sylvia Andrzejewski, Simon-Pierre Gravel, Michael Pollak, St-Pierre J: Metformin directly acts on mitochondria to alter cellular bioenergetics. Cancer & Metabolism 2014, 2(12):1-14.

              Possik E, Jalali Z, Nouët Y, Yan M, Gingras M-C, Schmeisser K, Panaite L, Dupuy F, Kharitidi D, Chotard Lt: Folliculin Regulates Ampk-Dependent Autophagy and Metabolic Stress Survival. PLOS genetics 2014, 10(4):e1004273.

            Poirier S, Samami S, Mamarbachi M, Demers A, Chang T-Y, Vance DE, Hatch GM, Mayer G: The epigenetic drug 5-Azacytidine interferes with cholesterol and lipid metabolism. Journal of Biological Chemistry 2014.

             Hamel D, Sanchez M, Duhamel Fo, Roy O, Honoré J-C, Noueihed B, Zhou T, Nadeau-Vallée M, Hou X, Lavoie J-C et al: G-Protein-Coupled Receptor 91 and Succinate Are Key Contributors in Neonatal Postcerebral Hypoxia-Ischemia Recovery. Arteriosclerosis, Thrombosis, and Vascular Biology 2014, 34(2):285-293.

           Gravel S-P, Andrzejewski S, Avizonis D, St-Pierre J: Stable Isotope Tracer Analysis in Isolated Mitochondria from Mammalian Systems. Metabolites 2014, 4(2):166-183.
        Chang C-H, Curtis JD, Maggi LB, Jr., Faubert B, Villarino A, O'Sullivan D, Huang SC-C, van der Windt GW, Blagih J, Qiu J et al: Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis. Cell 2014, 153(6):1239-1251.

          Faubert B, Vincent EE, Griss T, Samborska B, Izreig S, Svensson RU, Mamer OA, Avizonis D, Shackelford DB, Shaw RJ et al: Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1a. Proceedings of the National Academy of Sciences 2014.

             van der Windt GJW, O'Sullivan D, Everts B, Huang SC-C, Buck MD, Curtis JD, Chang C-H, Smith AM, Ai T, Faubert B et al: CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability. Proceedings of the National Academy of Sciences 2013, 110(35):14336-14341.

             Morita M, Gravel S-P, Chenard V, Sikstrom K, Zheng L, Alain T, Gandin V, Avizonis D, Arguello M, Zakaria C et al: mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation. Cell Metab 2013, 18(5):698-711.

         McGuirk S, Gravel S-P, Deblois G, Papadopoli D, Faubert B, Wegner A, Hiller K, Avizonis D, Akavia U, Jones R et al: PGC-1alpha supports glutamine metabolism in breast cancer. Cancer & Metabolism 2013, 1(1):22.

            Mamer O, Gravel S-P, Choiniere L, Chenard V, St-Pierre J, Avizonis D: The complete targeted profile of the organic acid intermediates of the citric acid cycle using a single stable isotope dilution analysis, sodium borodeuteride reduction and selected ion monitoring GC/MS. Metabolomics 2013, 9:1019–1030.

           Leprivier G, Remke M, Rotblat B, Dubuc A, Mateo A-R, Kool M, Agnihotri S, El-Naggar A, Yu B, Prakash SS et al: The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation. Cell 2013, 153(5):1064-1079.

        Hong E-J, Levasseur M-P, Dufour CR, Perry M-C, Giguere V: Loss of estrogen-related receptor alpha promotes hepatocarcinogenesis development via metabolic and inflammatory disturbances. Proceedings of the National Academy of Sciences 2013, 110(44):17975-17980.

        Faubert B, Boily G, Izreig S, Griss T, Samborska B, Dong Z, Dupuy F, Chambers C, Fuerth BJ, Viollet B et al: AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo. Cell Metab 2013, 17(1):113-124.

         Dupuy F, Griss T, Blagih J, Bridon G, Avizonis D, Ling C, Dong Z, Siwak DR, Annis MG, Mills GB et al: LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer. Cancer & Metabolism 2013, 1(18):16.

           Chaveroux C, Eichner LJ, Dufour CR, Shatnawi A, Khoutorsky A, Bourque G, Sonenberg N, Giguere V: Molecular and Genetic Crosstalks between mTOR and ERR-alpha Are Key Determinants of Rapamycin-Induced Nonalcoholic Fatty Liver. Cell Metab 2013, 17(4):586-598.

          Zakikhani M, Bazile M, Hashemi S, Javeshghani S, Avizonis D, Pierre JS, Pollak MN: Alterations in Cellular Energy Metabolism Associated with the Antiproliferative Effects of the ATM Inhibitor KU-55933 and with Metformin. PLoS ONE 2012, 7(11):e49513.

          Klimcakova E, Chenard V, McGuirk S, Germain D, Avizonis D, Muller WJ, St-Pierre J: PGC-1a Promotes the Growth of ErbB2/Neu‚ Induced Mammary Tumors by Regulating Nutrient Supply. Cancer Research 2012, 72(6):1538-1546.

           Javeshghani S, Zakikhani M, Austin S, Bazile M, Blouin M-J, Topisirovic I, St-Pierre J, Pollak MN: Carbon Source and Myc Expression Influence the Antiproliferative Actions of Metformin. Cancer Research 2012, 72(23):6257-6267.

         Christie DA, Mitsopoulos P, Blagih J, Dunn SD, St-Pierre J, Jones RG, Hatch GM, Madrenas Jn: Stomatin-like Protein 2 Deficiency in T Cells Is Associated with Altered Mitochondrial Respiration and Defective CD4+ T Cell Responses. The Journal of Immunology 2012, 189(9):4349-4360.

        O’Sullivan A, Avizonis D, German JB, Slupsky CM: Software Tools for NMR Metabolomics. In: Encyclopedia of Magnetic Resonance. vol. 10: John Wiley & Sons, Ltd; 2011.

          Argyropoulos D, Avizonis D: Electronic Referencing in Quantitative NMR. In: Encyclopedia of Magnetic Resonance. John Wiley & Sons, Ltd; 2010.